Polio-like virus discovered in US East Coast pigs

The newly identified virus was found in the central nervous tissues of young pigs and may have caused weakness in their hind legs.

This image, captured under a microscope, shows a section of brain and spinal cord with a severe inflammatory process. The tissues tested positive for the presence of the novel sapelovirus. Paulo Arruda | Iowa State University
This image, captured under a microscope, shows a section of brain and spinal cord with a severe inflammatory process. The tissues tested positive for the presence of the novel sapelovirus. Paulo Arruda | Iowa State University

A newly identified virus found in the central nervous tissues of young pigs may have caused the pigs’ polio-like weakness in their hind legs. A veterinary researcher at Iowa State University discovered the virus in pig tissue samples from near the US East Coast.

Paulo Arruda, an assistant professor of veterinary diagnostic and production animal medicine, led a team of diagnosticians from Iowa State, the University of Minnesota and Kansas State University in an effort to investigate samples from 11-week-old pigs that couldn’t walk due to a mysterious weakness in their hind legs.

Pig herd health impact of virus

The economic impact posed by the pig virus remains unclear, Aruda said. Farms dealing with the disease may lose 1 or 2 percent of pigs, making it a concern for individual pork producers, Arruda said in a press release.

Arruda said there’s no evidence the virus makes pork unsafe to eat.

Symptoms of previously unknown pig virus

The diagnostic team found microscopic lesions in the pigs’ central nervous system tissues containing a sapelovirus that researchers hadn’t previously encountered. Sapeloviruses belong to a family of viruses commonly found in pigs, but this particular strain was different from all other sapeloviruses previously described, Arruda said.

“We’re collecting evidence, sort of like in a forensic investigation,” he said. “But we still have a lot of questions that need to be answered about this virus.”

For instance, Arruda said despite the evidence collected, the team isn’t completely sure the virus is responsible for all the lesions in the spinal tissues or if there’s another unknown factor contributing to the neurological symptoms.

Range of the pig virus

The pigs originated on a farm near the East Coast, though Arruda said privacy concerns prevented him from identifying the specific operation.

Arruda said a lack of scientific evidence regarding the pig virus means it’s impossible to know just how widely it may spread. But the epidemiology of other viruses within its family leads Arruda to believe this particular strain may be fairly common on US hog farms. However, only a small percentage of pigs with the virus likely will display symptoms, he said.

The researchers used techniques such as gene sequencing to map the entire RNA and DNA genomes of pathogens within the samples. That data allowed the diagnosticians to conclude the pig virus was previously unidentified, or novel, and present in high numbers within the spinal cord samples of the affected pigs.

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