Adisseo has published Methiopedia - The Methionine Reference Book, intended for nutritionists, purchasers, formulators and technical managers within the premix and feed industries, as well as students, who want to enhance their knowledge of methionine and its use.

"Being one of the first companies to have synthesized powder methionine in the 40's, we considered that it could be of great interest to collect all the scientific information that Adisseo has gathered in research studies, trials and customer experience," says Pierre Casamatta, Adisseo global business director, methionine and sulfur products. "Adisseo experts have compiled information on methionine from around the world, including the latest developments, from fundamental research to in-vivo trials performed both in independent experimental facilities and on commercial farms."

The book offers a complete description of the three forms of methionine - L-methionine (L-Met), D,L-methionine (D,L-Met) and D,L-methionine hydroxy (D,L-HMTBA) - with their characteristics and properties. General chemical processes, metabolism and utilization of each form are detailed, and precise data on hydrolysis, absorption, and intestinal transport of these different sources are presented.

"Methiopedia includes research highlights on digestion and metabolism. Statistical models for dose-response are discussed," says Professor R.A. Swick, from the University of New England, Australia.


Besides physiological data, Methiopedia also provides a review of important animal performances (feed conversion, body weight gain) with practical diets including D,L-Methionine or D,L-HMTBA, especially for broilers. These recent data have been compiled from trials on animals conducted at different institutes across the world, such as BARC, (Bangkok Research Center), Thailand; The China Agricultural University, Beijing, China; IRTA, Spain; INRA, France, as well as Adisseo's facilities (CERN - Center of Expertise and Research in Nutrition - Commentry, France). "These trials and their meta-analysis show new evidence of the biological equivalency of both forms," says Pierre Dalibard, global technical manager, Adisseo.

Furthermore, the technical aspects of incorporating D,L-Met or D,L-HMTBA in feeds are developed by Adisseo experts in Methiopedia. They detail the different parameters involved in dosing and mixing accuracy, up to recovery tests, to ensure that the required level of methionine is reached in feed for powder and liquid forms.

Many technical results of recent trials carried out by Adisseo are provided in the book's appendix, which also contains a selection of relevant abstracts or articles on methionine presented at the latest Adisseo Advancia Seminars. Every year since 2007, these meetings gather worldwide scientists and nutritionists to share research progress on sulfur amino acids.