Campylobacter is one of the most important challenges for the European poultry industry. Despite considerable efforts, there is still no effective strategy available to prevent or reduce Campylobacter colonization in broilers.

The European Food Safety Authority has estimated that the public health benefits of controlling Campylobacter should be found in reducing the bacterial load in the broiler intestinal tract at the end of the finishing period. Reducing Campylobacter in the broiler intestine at slaughter age with 2 or 3 log10 CFU is believed to reduce public health risk with 76 percent or 90 percent respectively.

Campybro is a large European-funded project to investigate strategies to control Campylobacter infections in broiler flocks through vaccination and nutrition. The project is a collaboration between research institutes Imasde and the French Agency for Food, Environmental and Occupational Health & Safety, along with major European organizations and stakeholders in the poultry industry such as the Poultry Board in Budapest, Mikrolab and Nepluvi.

One of the first studies of the Campybro project evaluated the effect of different feed additives on broilers infected with Campylobacter. The probiotic Calsporin®, distributed by Orffa Additives, was one of the three treatments showing a significant reduction of Campylobacter at day 42, slaughter age. In a second study the research group evaluated the combination of a blend of mono-glycerides and organic acids (MGOA) with Calsporin®. Over the whole period the treatment with MGOA and Calsporin significantly reduced ceacal Campylobacter counts, with a decrease of 4 log10 CFU reached at slaughter weight.

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The pathogenesis of Campylobacter is complicated and still poorly understood despite all research activities. Calsporin is known to have a beneficial effect on the intestinal microflora, thereby reducing harmful gut bacteria. The promising results of this project are in line with earlier obtained data, which indicates that Calsporin could be an interesting tool in a solution to control Campylobacter in broiler flocks.

Calsporin (Bacillus subtilis C-3102) is a European authorized probiotic produced by Asahi Calpis Wellness.

Publication of the results can be found at: 
Poultry Science, online publication Dec 2015
ESPN, proceedings 2015, poster presentations P-014