Sponsored by Ceva Santé Animale

 

NATIVE_Ceva_brown layerThe best option to control IBD is to use a live attenuated IBD vaccine, which is capable of reaching the bursa and generate a high level of protection against various types of IBD viruses and effectively preventing shedding. This way, the virus pressure decreases cycle after cycle, and the likelihood of the emergence of virulent variant IBDV can be strongly reduced. The Immune complex (Icx) technology has been used extensively in broilers for many years. The Icx vaccine is injected at the hatchery and ensures 100% coverage with the correct dose. However, this technology was not available for pullets since the decay of MDAIBDV of slow-growing birds differs from the fast growing-type bird (Shown in the graph below).

NATIVE_Ceva_novamune graph

Novamune® is the first IBD immune complex vaccine designed specifically for layer pullets. It consists of an IBD virus strain (the SYZA-26) bonded by specific antibodies called Virus Protecting Immunoglobulins.  Novamune® is injected on day 1 at the hatchery.

NATIVE_Ceva_novamune VPI

How does Novamune® immunize the pullet?

From the first day, the MDAIBDV levels will decrease. The decay is variable according to the starting MDAIBDV level at hatch. The vaccine take occurs when the MDAIBDV level drops to a point where it will no longer prevent the SYZA 26 from reaching the bursa of Fabricius.

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NATIVE_Ceva_novamune MDA levels

Once SYZA-26 reaches the bursa, it will replicate quickly, preventing the replication of any other IBDV strain. The SYZA-26 replication will induce a fast and robust active immune response.

NATIVE_Ceva_novamune protection level

Specific Potency Test – Chick Infective Dose -50 (CID 50)

As the vaccine is registered in Europe, a unique quality control procedure was developed by Ceva to safeguard the efficacy and safety of Novamune. Every batch is tested using a CID-50 test. This technique is used to access the potency and safety of the final product (blended vaccine).

NATIVE_Ceva_transmune IBD