Sponsored by Ceva Santé Animale


For many years, layer producers have been vaccinating their pullets against Gumboro Disease through drinking water and, most recently, rHVT IBD. Due to inadequate vaccine take or inability to replicate in the BF, these types of vaccines cannot prevent the replication of field virus in this primary lymphoid organ, consequently preventing the shedding of the field virus to the environment.  The take of Novamune (that corresponds to replication of the vaccine strain in the BF) occurs when the passive immunity against IBDV level reaches a level allowing the vaccine to take before the flock becomes susceptible to the infection by the field IBD virus. The bursa colonization by SyZA-26 prevents the infection and shedding of the field virus, therefore STOPPING The Gumboro Cycle in the pullet house.

NATIVE_Ceva_stop gomburo logo• Full protection against clinical signs, high degree of resistance against infection whatever the challenging IBDV strain;

• Reduce shedding, no selection pressure on the farm' IBDV population;

• The vaccine adapts individually to the immune status of each pullet and replicates at the 'optimum' time;

• The vaccine can be administered in the presence of passive immunity, so it does not contradict and may even complement the breeders' program;

• The vaccine is injected in the hatchery, so reliability and consistency of application is at a maximum. Every pullet benefits from the properties of the vaccine.

Novamune®, associated with outstanding Ceva hatchery services and Veterinary services, makes a comprehensive package to STOP The Gumboro Cycle.

NATIVE_Ceva_GPS logo• Ceva Hatchery Immunization Control Keys (CHICK.) Program;


• Ceva Global Protection Services (G.P.S.).

Gumboro Control from the hatchery

As described above, using a live IBD vaccine is essential to control the Gumboro Cycle, as the vaccine strain will replicate in the bursa. However, the IBD vaccination at the farm via drinking water or, in some cases, via spray is very challenging. Many pullets may not get the vaccine or receive a suboptimal dose.

A single injection with Novamune® in the hatchery will replace multiple IBD vaccination at the farm. It makes the process of vaccination much simpler and accurate. On top of that, the vaccine preparation and application are performed by properly trained (following Ceva's SOPs) hatchery personnel. The process is also audit regularly by the Ceva hatchery vaccination team.


Flexibility in the hatchery

Another advantage of using the Icx technology in pullets is the possibility of combination with vectorized vaccines against Newcastle (rHVT ND), Laringotracheitis (rHVT ILT), or Avian Influenza (rHVT AI).

Novamune® is also compatible with CVI988 Rispens vaccine.

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Convenience & Flexibility

Novamune® + Vectormune® ND compatibility was evaluated in commercial layer pullets. The vaccines were applied by subcutaneous injection at day of age. Serology for IBD and ND were performed weekly to access vaccine immune response in combining products and both products alone. See results in the table below.

NATIVE_Ceva_Novamune and Vectormune

Protection & Reduction of Shedding

The efficacy of Novamune® was evaluated by challenging vaccinated birds with a very virulent IBDV strain. In this study, the spread of challenge strain from infected chickens to contact control birds were also monitored. Methodology Day-old commercial pullets were vaccinated with Novamune® and challenged at 35 days with a very virulent IBDV strain. Two days post-challenge, contact birds (not vaccinated, not challenged) were co-housed among NOVAMUNE® group pullets. Measurement of challenge virus replication (RT-PCR & Histopathology), morbidity, and mortality were evaluated on all groups. Source: Ceva internal study, SSIU PI019, 2018.

NATIVE_Ceva_Novamune infographic