Genetic engineering technology could generate a layer breed that produces only non-GMO layer hens, which could help reduce or even eliminate male chick culling at layer farms.

“We have developed a system which allows us to modify the chicken genome in a very accurate and desired way,” said Yuval Cinnamon, a principal investigator at the Agricultural Research Organization, The Volcani Center, NRS Poultry Sustainability and Transformation

“We can introduce a trait which stops embryogenesis at a very early stage, all male embryos will cease to develop and will no longer hatch. Excluding male eggs from the incubators will save 50% of the space and energy, thus benefiting sustainability."

Approximately 6-7 billion male layer chicks are culled each year, a major animal welfare and economic concern for the layer industry. Animal welfare organizations have pressured the egg industry to find an alternative approach.

Cinnamon is one of the many experts scheduled to speak at the Poultry Tech Summit, scheduled for October 31 – November 2, 2021. This one-of-a-kind in-person and on-demand event facilitates the transition of innovation technologies from researchers and entrepreneurs into commercial applications for the benefit of the poultry industry. Make plans to attend and take a look at the future of the industry.

Registration for the 2021 Poultry Tech Summit is now open.

How it works

In chickens and other birds, sex is determined by a ZZ:ZW sex chromosome system. Unlike the XY sex chromosome system in humans, females have a pair of dissimilar chromosomes (ZW), while the males have two similar chromosomes (ZZ).


Using genetic engineering, the research team created a breeding flock with hens harboring a lethality embryonically inducible gene located on the maternal Z chromosome. Upon activation of the gene by blue light illumination, male embryonic development is stopped very early in development. 

The females receive a wildtype W sex chromosome for the mother hen and wildtype Z chromosome from a normal male, which means the female chicks contain no modified genetic material and are genetically identical to the hens currently used by the egg industry.

“The challenge of generating genetically transformed chickens is very difficult. It’s not like generating other genetically modified organisms like mammals,” Cinnamon explained. “It begins with in-silico research, which is bioinformatics, through tissue culture, molecular biology, genetic engineering and gene editing using CRISPR technology, all the way to chicken production.”

Attend the 2021 Poultry Tech Summit

Join an exclusive international gathering of industry-changing innovators, researchers, entrepreneurs, technology experts, investors and leading poultry producers at the 2021 edition of Poultry Tech Summit on October 31 - November 2 in Atlanta, Georgia. Attendees can expect the same groundbreaking innovation and insightful presentations that made the previous events well-attended with deep dialogue on new prospective solutions and developing technologies.

Early Bird registration is now open.

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