AgriLabs ExactVac is a DNA vaccine approved for influenza for veterinary use in chickens. The vaccine is produced by splicing a gene for a specific antigen related to an avian influenza high pathogenic H5 subtype into a bacterial plasmid. The plasmid is then multiplied, purified and administered along with the ENABL adjuvant that improves vaccine delivery into target cells, where antigens produced by the plasmid elicit an immune response. The conditional license for high pathogenic H5 provides a tool for U.S. poultry producers if stockpiling is needed for future avian flu outbreaks.

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