Jonathan Broomhead, Ph.D., manager of global poultry research and technical support at Diamond V, shared insights on reducing pathogen stress by improving gut health during the opening ceremony of the new Diamond V Layer Research Unit. The unit is located in the Animal Science Learning Center of the Department of Animal Science on the Kamphaeng Saen Campus of Kasetsart University in Nakhon Pathom, Thailand.


Diamond V, a global nutrition and health company, manufactures all-natural products that promote animal health and performance. It connects unique competencies in microbial-based fermentation with specie-specific expertise and world-class research to create profitable solutions for customers worldwide. 
Microbial fermentation products continue to gain increasing attention as one of several non-antibiotic gut health products. As a category, non-antibiotic gut health products have either a direct or indirect effect on pathogens.
"Research has shown that Diamond V Original XPC, a product of anaerobic fermentation, contains a diverse metabolite package," said Broomhead. "It has the unique ability to optimize innate immune function, antibody production, and gut morphology. In addition, its prebiotic-like activity improves microbial balance in the gut. Prebiotics have the advantage of feeding the endogenous beneficial bacteria that are naturally found in the GI system of birds."
Broomhead cited research that indicates poultry stress could be reduced by feeding Original XPC. The balance of intestinal microbiota improves when beneficial bacteria colonization is enhanced, resulting in pathogenic bacteria facing competitive exclusion. In addition, short-chained fatty acid production improves as a result of fermentation by beneficial bacteria. Increased short-chained fatty acids can modify the intestinal environment and suppress pathogen colonization. Optimizing immune function helps reduce systemic inflammation associated with a robust innate immune response and improves adaptive immunity.
In summary, Dr. Broomhead described the mode of action for Original XPC as three-pronged: improving the microbiota by enhancing the populations of beneficial bacteria, promoting the gut's morphology which strengthens gut integrity and helps heighten feedstuff digestion, and balancing immunity. Balanced immunity includes both innate and adaptive immunity, improving antibody (vaccine) titers, antioxidant levels, and anti-inflammatory activity.
  The Animal Science Learning Center provides training for undergraduate and graduate students in livestock production under tropical conditions.  It recognizes that trends in livestock production are directly influenced by changes in global economic, political, climate and consumer demands. Good training and preparation are needed to establish a strong and sustainable livestock industry.